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Diverse Responses to Cytomegalovirus Drive the Need for Population-Specific Treatment Approaches

Amanda Stevenson-Grund - Friday, September 29, 2017

Born This Way: Congenital Cytomegalovirus

Amanda Stevenson-Grund - Friday, September 15, 2017

About one out of every 200 babies are born with congenital CMV infection.”
 –
CDC, Cytomegalovirus (CMV) and Congenital CMV Infection. Accessed May 6, 2017

Pediatric patients with congenital cytomegalovirus can experience physical disabilities

Most parents of newborn babies experience joy when welcoming a new member of the family. However, parents of children with congenital cytomegalovirus instead experience the fear that their children may be affected by the physical and intellectual disabilities that can accompany this disease. In very extreme cases, congenital cytomegalovirus can lead to death in newborns and young children.

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Strengthening Solubility: Advantages of Increased Drug Solubility

Amanda Stevenson-Grund - Friday, September 01, 2017

Poorly water-soluble drug candidates are becoming more prevalent. It has been estimated that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous media,”Gupta et al., Formulation Strategies to Improve the Bioavailability of Poorly Absorbed Drugs with Special Emphasis on Self-Emulsifying Systems. ISRN Pharmaceutics: 2013; 2013

 

Poorly water soluble drugs continue to pose significant formulation challenges. Solubility challenges have driven CDMOs to employ a portfolio of technologies to address solubility challenges. 

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