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Obviously Orodispersible: When ODTs are a Good Fit

Amanda Stevenson-Grund - Friday, August 11, 2017

Orodispersible tablets (ODT) can be administered to any patients having difficulty in swallowing.” – Hannan, et al. Indian J Pharm Sci. 2016; 78: 2-7

A pediatric patient with dysphagia and low medication adherence takes an orodispersible tablet (ODT).

Demand for patient-friendly formulations is increasing to address the diverse needs of multiple patient populations. As demand increases, pharmaceutical companies continue to look for innovative solutions to meet a broad range of patient needs. Orodispersible tablets (ODTs) can be a good fit for pediatric patients, geriatric patients and patients with dysphagia, as well as patients with low medication adherence.

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The Power of Powder: Dispersible Powder and Its Many Formats

Amanda Stevenson-Grund - Friday, July 28, 2017

Powders and granules may be given to children from birth provided they can be administered as a liquid preparation.” – European Medicines Agency, Guideline on pharmaceutical development of medicines for paediatric use. 2013: 7

Medication in powder format

Powder medications predominate in many countries, such as Finland and Italy, and are starting to grow in popularity in the United States, according to Brion et al. in Acta Paediatrica. The power of powder lies in its many formats and kid-friendly features.

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Extended Release in Parenteral Drugs: Designed with Patients in Mind

Amanda Stevenson-Grund - Friday, July 14, 2017

Several solutions to the problem of discontinuous access to pharmacotherapy are being developed in the form of new, long-acting drug-delivery systems, which gradually release medication over a period of several days or weeks with a single application.” – Siegel, Psychiatry (Edgmont). 2005; 2: 22-31

 A patient holds an extended-release parenteral drug

Like a tailored suit, some things just fit well. This is true in pharmaceuticals. Drugs with certain characteristics are often a good fit for specific conditions and diseases. For example, extended-release parenteral drugs have many benefits, which make them good candidates for psychiatric conditions and chronic pain.

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We Go Together Like Parenteral Drug Delivery and Certain Drug Properties

Amanda Stevenson-Grund - Friday, June 30, 2017

“Parenteral drug administration, in which a drug is introduced directly across the body’s barrier defenses into the systemic circulation or some other tissue space, immediately overcomes barriers that can limit the effectiveness of orally administered drugs.” - Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. Edited by David E. Golan, Lippincott Williams & Wilkins, 2008

A syringe represents drug delivery in parenteral drugs

Peanut butter and jelly, peas and carrots, Kirk and Spock – all are common examples of great combinations. A great pairing is also important when it comes to parenteral drug delivery and the medications delivered via this route. Drugs that are well-suited for parenteral drug delivery are those that are not bioavailable when administered orally, that are destroyed by digestive enzymes or that are irritating when delivered via other routes of administration.

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Your Best Shot: Types of Parenteral Drug Delivery Methods

Amanda Stevenson-Grund - Friday, June 16, 2017

Injections are among the most common health care procedures throughout the world, with at least 16 billion administered in developing and transitional countries each year.”
Jin, et al. Patient Prefer Adherence. 2015; 9: 923

A syringe represents the types of parenteral drugs in drug delivery

A big shot is someone important. However, in the medical field, all types of shots, or injectable or parenteral administration methods, are important. The three most common types of parenteral drugs are intramuscular, subcutaneous and intravenous.

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Perfectly Parenteral: Advantages of Parenteral Drug Delivery

Amanda Stevenson-Grund - Friday, June 02, 2017

The evident advantages of parenteral injection are the reliability and precision of dosage and the generally rapid onset of action of the drug,” – Schou, “Chapter 4: Subcutaneous and Intramuscular Injection of Drugs.” Concepts in Biochemical Pharmacology, Part 1. 1971; 28: 47

A parenteral drug like this one can improve adherence

Patients and caregivers of patients who are afraid of needles may wonder why any medication is given in the form of shots. However, parenteral drug delivery has unique advantages. Parenteral drugs can improve adherence, act immediately and allow the administrator to control drug delivery.

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Sachets Are Working Out in Drug Delivery

Amanda Stevenson-Grund - Friday, May 19, 2017

It is no wonder, then, that by 2018, up to 50 percent of all flexible pharmaceutical packaging will be in sachet or stick pack format.” – Bühler. Packaging Europe. 2015

Sachets are a flexible form of drug delivery

Sachets are the gymnasts of drug administration. This is because sachets are a flexible form of drug delivery. Their contents can go into food, hot drinks and feeding tubes.

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The Sense in Sachets

Amanda Stevenson-Grund - Friday, May 05, 2017

A key reason sachet packed medication is the fastest growing Dose Administration Aid (DAA) in the world, is that they offer a range of benefits which aged-care operators and community customers consider important.Amcal Chempro Chemists. Packing. Accessed August 31, 2016

A sachet for use in drug delivery

Sachets are a growing trend in drug delivery right now and for good reason. There are many benefits to using sachets in drug delivery. Three reasons drug developers use sachets are the allowance for high doses, format flexibility and minimization of harm during drug crushing.

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Sachets in Drug Delivery - A Growing Trend

Amanda Stevenson-Grund - Friday, April 21, 2017

“Companies are increasingly focusing on the development of orally disintegrating tablets (ODTs) and other novel methods of oral drug delivery. There is also a growing trend towards the formulation of sachets.” – Research and Markets, Global Pharmaceutical Excipients Market 2016-2021 – Type, Functionality, Formulation Analysis of the $8.1 Billion Industry. 2016

Sachets are a growing trend in drug delivery

“Disruptive” is the current business jargon for a product or service that changes a market. Most organizations want to “disrupt” their industries, with the hope it will affect the market permanently. In healthcare, an example is the increasing use of sachets in drug delivery. Sachets are now being used to treat all types of diseases, from the common cold to solid tumor cancers.

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Putting Patients in Control: How Controlled-release Drugs Help Patients

Amanda Stevenson-Grund - Friday, April 07, 2017

Controlled-release (CR) drug-delivery systems continue to play an important role in the treatment of diseases” – Slew, Pharmaceutical Technology. 2014: 38

Controlled-release drugs help patients by reducing drug burst, reducing interruptions to daily life and improving medication adherence.

The Gettysburg address states that government should be “by the people, for the people.” Medication should also be created for the people. The best medicine is that developed for the specific needs of the patient. Controlled-release drugs help patients by reducing drug burst, reducing interruptions to daily life and improving medication adherence.

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